Mass spectrometry

Mapping Glycobiology in Depth and in Space
Unlock the full complexity of glycans with integrated mass spectrometry—combining glycomics, glycoproteomics, and spatial imaging to reveal structure, function, and location for breakthroughs in health and disease.

Mass spectrometry-based omics and imaging enable deep insights into molecular glycobiology. BioBeyond_NL provides access to unique infrastructure and knowledge to enable scientists to advance their research. Our mass spectrometry platforms provide complementary high-resolution insights into carbohydrate structures in biological systems. Glycomics profiles the full repertoire of glycans, revealing structural changes upon perturbation of a biological system. Glycoproteomics provides complementary information by characterizing site-specific glycosylation profiles on individual proteins. MS imaging localizes glycans within tissues, preserving spatial context that is essential for understanding cell-type and microenvironment-specific glycosylation. Together, these platforms uncover unique insights into glycobiology mechanisms that support development of technical and (pre-)clinical applications such as biomarker discovery and therapeutic target identification in life science disciplines such as cancer, immunology and metabolic disorders, and Beyond.