BioBeyond_NL
Unlock the full complexity of glycans with integrated mass spectrometry – combining glyco chemistry, glycoproteomics, and spatial imaging to reveal structure, function, and location for breakthroughs in health and disease.
Glycomics is the study of glycans: complex sugars present on cells, proteins and lipids. These branched molecular structures play a role in various biological processes like cell-to-cell communication, immunity, adhesion, differentiation or disease processes like cancer or inflammation.
The field of glycomics studies the presence, abundance, structure and spatial orientation of these glycans in various biological and disease models. Through mass spectrometry, imaging and data science, researchers can uncover unique insights into glycobiology mechanisms that support development of technical and (pre-)clinical applications such as biomarker discovery and therapeutic target identification in life science disciplines such as cancer, immunology and metabolic disorders, and Beyond.
BIOBEYOND_NL
BioBeyond_NL is a large-scale national infrastructure providing access to academic and industrial users to high-end, state-of-the-art technologies, knowledge and support to study glycobiology. Within the infrastructure, mass spectrometry and glycoscience is merged, enabling researchers to investigate these (bio)molecules and to elucidate their function in the context of their natural environment, in greater molecular, spatial, and temporal detail.
BioBeyond_NL comprises of four key state-of-the-art infrastructural elements to provide a complete and integrated solution for (inter)national scientists to mine elusive biomolecular information:
- Glyco Imaging
- Glyco chemistry
- Glcyo Proteomics
- Integrative Data Science
These four synergistic innovations are spearheaded by Dutch experts in proteomics, MS imaging, glycobiology and data science, who have exceptional track records in research and have provided access to their infrastructures in the Netherlands and Europe for over 15 years. They will expand on and integrate existing LSRIs and European infrastructures, but with new and innovative investments in the foundational national mass spectrometry and glycochemistry infrastructure.
USING THE BIOBEYOND_NL INFRASTRUCTURE
We welcome all academic and industrial users to our infrastructure.
If you are interested in using our facilities or discuss what are the possibilities for your glycomics research, come into contact with us via email info@biobeyond.nl.
Maastricht University (UM)
www.maastrichtuniversity.nl
Utrecht University (UU)
www.uu.nl
Radboud University (RUMC)
www.radboudumc.nl
Leiden University Medical Center (LUMC)
www.lumc.nl